Metamoodics Gene Information

 

  Chromosome: chr10    Cytoband: p12.1    Gene: GPR158

 

BP - Genomewide Expression Studies for GPR158


 

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Description

 
Shown here are the results for gene GPR158 from a meta-analysis of genomewide expression studies of bipolar disorder using microarrays with autopsy brain samples from humans. Details of the methods for carrying out the meta-analysis are provided here.

 

 

Results Figure

 
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Figure Legend: The figure shows a Forest Plot with the estimated fold change of gene expression comparing cases and controls and 95% confidence interval for each study. Summary estimates are provided for all studies, studies with samples from the pre-frontal cortex, studies with samples specifically from BA46 of the pre-frontal cortex, and from the hippocampus. Details of the results are provided in the Results Table below.

 

 

Results Table

 

 

 

STUDYBRAIN_REGIONARRAY_PLATFORMSEBETA_EST.FC95%_CIPVALFDR_PVALPROBESET
ChenFrontalBA46HGU133P0.0654-0.0304-1.02[-1.12,1.07]0.6460.958232195_at
DobrinFrontalBA46HGU133P0.0496-0.0202-1.01[-1.08,1.05]0.6860.983232195_at
KemetherThalamusHGU133P0.0532-0.1344-1.1[-1.18,-1.02]0.01960.701232195_at
LaengHippocampusHGU133P0.0460.0532 1.04[-1.03,1.1]0.2550.999232195_at
          
megaanalysisAny_BrainHGU1330.0271-0.0204-1.01[-1.05,1.02]0.4520.889 
 
* Additional studies not included in megaanalysis     

 

 

References

 

Systematic Review of Genome-wide Gene Expression Studies of Bipolar Disorder Fayaz Seifuddin, Mehdi Pirooznia, Jennifer T. Judy, Fernando S. Goes, James B. Potash and Peter P. Zandi. Manuscript submitted.