Metamoodics Gene Information


  Chromosome: chr10    Cytoband: q23.31    Gene: HTR7


BP - Genomewide Expression Studies for HTR7


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Shown here are the results for gene HTR7 from a meta-analysis of genomewide expression studies of bipolar disorder using microarrays with autopsy brain samples from humans. Details of the methods for carrying out the meta-analysis are provided here.



Results Figure


Figure Legend: The figure shows a Forest Plot with the estimated fold change of gene expression comparing cases and controls and 95% confidence interval for each study. Summary estimates are provided for all studies, studies with samples from the pre-frontal cortex, studies with samples specifically from BA46 of the pre-frontal cortex, and from the hippocampus. Details of the results are provided in the Results Table below.



Results Table




Harvard.HippHippocampusHGU95AV20.08530.0031 1[-1.12,1.13]0.9720.99134634_s_at
* Additional studies not included in megaanalysis     
FeinbergCerebellumHGU95AV20.03380.0393 1.03[-1.02,1.08]0.2573200.91234634_s_at
KatoBFrontalBA10HGU95AV20.04870.1005 1.07[1.00,1.15]0.0500550.39534634_s_at
SklarBCerebellumHGU95AV20.08950.0197 1.01[-1.11,1.14]0.8280860.99534634_s_at
SokolovTemporal.CortexHGU95AV20.04660.0556 1.04[-1.03,1.11]0.2456880.78734634_s_at





Systematic Review of Genome-wide Gene Expression Studies of Bipolar Disorder Fayaz Seifuddin, Mehdi Pirooznia, Jennifer T. Judy, Fernando S. Goes, James B. Potash and Peter P. Zandi. Manuscript submitted.