Metamoodics - BP Linkage

Metamoodics Gene Information

Chromosome: chr6

Cytoband: q23.3

Gene: MAP3K5

BP - Genomewide Linkage Studies for MAP3K5

Shown here are the results for gene MAP3K5 from a genomewide linkage mega-analysis of bipolar disorder carried out with 972 informative pedigrees of European ancestry pooled from eight research groups in North America and the United Kingdom and genotyped on the Illumina Linkage Panel 12 consisting of 6090 SNPs.

Details of the methods for the linkage analysis are provided in methods section.

Results Figure

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Figure Legend: Graphical display of linkage analysis results for 12 different phenotype by genotype models across the chromosome. The yellow line marks the location of the selected gene on the chromosome, and the white window shows 20 Mb around the gene.

Phenotype Models
ASMI: Affecteds include bipolar I and schizoaffective manic sub-type disorders
ASMII: Affecteds include ASMI plus bipolar II disorders
ASMIII: Affecteds include ASMII plus recurrent major depression

Genetic Models
Dom_HLOD: Parametric heterogeneity dominant model (risk allele frequency 0.01, penetrances 0.01, 0.70, 0.70)
Rec_HLOD: Parametric heterogeneity recessive model (risk allele frequency 0.1, penetrances 0.01, 0.01, 0.70)
Exp_LOD: Non-parametric linkage (NPL) analysis with SAll under the exponential model
Pairs_LOD: Non-parametric linkage (NPL) analysis with SPairs under the linear model

Results Table

Marker

pos_bp (hg18)

pos_cM

Gene(s)

ASMI

ASMII

ASMIII

Dom_H

Rec_H

Exp

Pairs

Dom_H

Rec_H

Exp

Pairs

Dom_H

Rec_H

Exp

Pairs

rs719065	chr6:110632	0.0267		0.039	0.049	0.081	0.041	0	0.02	-0.079	-0.059	0	0.029	-0.289	-0.209
rs1986818	chr6:133969	0.0323		0.039	0.049	0.081	0.041	0	0.02	-0.079	-0.059	0	0.029	-0.288	-0.209
rs727056	chr6:170044	0.041		0.039	0.049	0.081	0.041	0	0.02	-0.079	-0.059	0	0.029	-0.288	-0.209
rs6922081	chr6:199337	0.0844		0.041	0.05	0.082	0.042	0	0.021	-0.077	-0.057	0	0.029	-0.286	-0.207
rs4960355	chr6:775293	2.228		0.137	0.055	0.142	0.08	0	0.035	-0.018	-0.018	0	0.025	-0.18	-0.132
rs1055368	chr6:852550	2.4979		0.144	0.054	0.145	0.08	0	0.038	-0.015	-0.015	0	0.025	-0.18	-0.135
rs10793833	chr6:1235388	3.8432		0.186	0.039	0.167	0.088	0	0.049	-0.002	-0.002	0	0.018	-0.18	-0.148
rs1013303	chr6:1694927	5.3767	GMDS	0.254	0.056	0.26	0.156	0	0.094	0.011	0.011	0	0.022	-0.125	-0.115
rs234915	chr6:2154576	6.8263	GMDS	0.326	0.101	0.384	0.283	0	0.139	0.047	0.055	0	0.038	-0.067	-0.057
rs9328112	chr6:2596986	8.1242		0.309	0.107	0.423	0.328	0	0.128	0.054	0.063	0	0.071	-0.066	-0.057
rs7775474	chr6:3413223	10.306		0.054	0.022	0.058	0.031	0	0.07	-0.003	-0.01	0	0.096	-0.177	-0.18
rs190129	chr6:3663360	11.0243		0.03	0.025	0.029	0.01	0	0.079	-0.01	-0.01	0	0.111	-0.17	-0.18
rs2025267	chr6:4103521	12.2675		0.014	0.037	0	0	0	0.093	-0.017	-0.027	0	0.127	-0.152	-0.185
rs1411653	chr6:4374381	13.0379		0.015	0.043	0	0	0	0.09	-0.01	-0.02	0	0.127	-0.128	-0.169
rs429909	chr6:4610134	13.6515		0.022	0.033	0.007	0	0	0.063	-0.003	-0.02	0	0.108	-0.097	-0.15
rs2032985	chr6:5354290	15.562	FARS2	0.033	0.001	0.01	0	0.005	0.002	0	-0.03	0	0.048	-0.028	-0.098
rs6597161	chr6:5680206	16.3338	FARS2	0.034	0	0.017	0	0.01	0	0	-0.03	0	0.024	-0.007	-0.073
rs4960147	chr6:5897590	16.9005		0.03	0	0.028	0	0.011	0	0	-0.03	0	0.016	-0.001	-0.062
rs3823193	chr6:6114217	17.4434	F13A1	0.025	0	0.034	0	0.006	0	0	-0.034	0	0.02	0	-0.056
rs1902944	chr6:6304489	17.8686	LY86-AS1	0.021	0	0.039	0	0.001	0	0	-0.039	0	0.025	0	-0.051
rs1892512	chr6:6923632	19.4375		0.013	0	0.044	0.004	0	0	0	-0.044	0	0.027	-0.014	-0.064
rs2763122	chr6:7426927	20.6004		0.018	0	0.068	0.016	0	0	0	-0.05	0	0.021	-0.02	-0.076
rs2815155	chr6:8010229	21.8249	EEF1E1-MUTED	0.036	0	0.105	0.028	0	0	0	-0.034	0	0.01	-0.02	-0.088
rs505567	chr6:8223804	22.2561		0.038	0	0.107	0.027	0	0	0	-0.033	0	0.006	-0.023	-0.098
rs1410766	chr6:8470359	22.7494	LOC100506207	0.035	0	0.103	0.023	0	0	0	-0.037	0	0.002	-0.027	-0.112
rs6597349	chr6:8699958	23.1946	LOC100506207	0.027	0	0.086	0.016	0	0	-0.002	-0.052	0	0	-0.038	-0.13
rs2876143	chr6:8928623	23.6415		0.012	0	0.055	0.007	0	0	-0.006	-0.078	0	0	-0.056	-0.152
rs767022	chr6:9084652	23.94		0.002	0	0.034	0.001	0	0	-0.009	-0.096	0	0	-0.068	-0.167
rs761116	chr6:9566315	24.8951		0	0.002	0.012	0	0	0	-0.019	-0.118	0	0	-0.106	-0.17
rs1328132	chr6:9879077	25.4944		0	0.002	0.005	-0.005	0	0	-0.05	-0.155	0	0	-0.145	-0.195
rs6925615	chr6:10147044	26.0025		0	0.001	0	-0.01	0	0	-0.08	-0.19	0	0	-0.18	-0.22
rs760892	chr6:10166797	26.0411		0	0.001	0	-0.011	0	0	-0.08	-0.188	0	0	-0.176	-0.215
rs560194	chr6:10636780	26.9323	GCNT2	0	0	0	-0.029	0	0	-0.071	-0.153	0	0	-0.087	-0.108
rs1225732	chr6:11042556	27.617	SYCP2L	0	0	0	-0.018	0	0	-0.045	-0.107	0	0	-0.043	-0.063
rs561332	chr6:11718567	28.9946		0	0	0	0	0	0	-0.01	-0.05	0	0	0	-0.01
rs6926835	chr6:12335531	30.3541		0	0	0.017	0.004	0	0	0	-0.006	0	0	0	0
rs1953088	chr6:13033922	31.823	PHACTR1	0	0	0.055	0.018	0	0	0.008	0	0	0	0	0
rs1150613	chr6:13288350	32.2656	PHACTR1	0	0	0.063	0.023	0	0	0.013	0	0	0	0.003	0
rs1863995	chr6:13565596	32.6846	GFOD1	0	0	0.067	0.027	0	0	0.017	0	0	0	0.007	0
rs707816	chr6:13742961	32.8742	RANBP9	0	0	0.069	0.029	0	0	0.019	0	0	0	0.009	0
rs1555020	chr6:14574707	34.1436		0	0	0.176	0.114	0	0	0.117	0.044	0	0	0.114	0.043
rs1891284	chr6:14760147	34.5539		0	0	0.192	0.127	0	0	0.138	0.057	0	0	0.127	0.051
rs1259078	chr6:15123286	35.3574		0	0	0.221	0.144	0	0	0.192	0.088	0	0	0.169	0.078
rs752861	chr6:15381231	35.8579	JARID2	0	0	0.236	0.149	0	0	0.237	0.113	0	0	0.209	0.103
rs74111	chr6:15894581	36.6095		0	0	0.24	0.15	0	0	0.262	0.132	0	0	0.263	0.14
rs6900454	chr6:16653636	37.8025	ATXN1	0	0	0.224	0.134	0	0	0.262	0.124	0	0	0.29	0.16
rs6901750	chr6:17127405	38.9284		0	0	0.146	0.065	0	0	0.176	0.074	0	0	0.197	0.095
rs10949418	chr6:17469390	39.7831		0	0	0.124	0.052	0	0	0.162	0.062	0	0	0.167	0.082
rs214527	chr6:18399329	41.3795		0	0	0.166	0.08	0	0.016	0.208	0.09	0	0	0.16	0.072
rs2008687	chr6:19283673	42.1083		0	0	0.161	0.082	0	0.022	0.231	0.098	0	0	0.17	0.07
rs1011119	chr6:19972144	42.7584		0	0	0.168	0.095	0	0.024	0.296	0.143	0.002	0	0.228	0.128
rs965037	chr6:20098951	42.9123		0	0	0.169	0.098	0	0.024	0.311	0.154	0.002	0	0.242	0.142
rs911361	chr6:20523032	43.4893	E2F3	0	0	0.155	0.095	0	0.015	0.3	0.16	0.005	0	0.255	0.16
rs1498426	chr6:21116132	44.2377	CDKAL1	0	0	0.14	0.09	0	0.004	0.278	0.16	0.007	0	0.248	0.168
rs2180419	chr6:21836296	45.4801	LINC00340	0	0	0.14	0.085	0	0	0.246	0.136	0	0	0.176	0.131
rs6456488	chr6:22557775	46.9866		0	0	0.13	0.07	0	0	0.151	0.061	0	0	0.061	0.041
rs11754333	chr6:23301033	48.2028		0	0	0.164	0.098	0.039	0	0.178	0.068	0	0	0.062	0.052
rs197987	chr6:23701197	48.7252		0	0	0.148	0.093	0.04	0	0.173	0.063	0	0	0.067	0.057
rs1355460	chr6:23999853	49.1919		0	0	0.153	0.103	0.037	0	0.176	0.066	0	0	0.078	0.07
rs1402405	chr6:24198476	49.5254		0	0	0.177	0.127	0.032	0.001	0.186	0.076	0	0	0.091	0.086
rs159988	chr6:25189466	51.3319	CMAHP	0	0	0.287	0.263	0.016	0.026	0.233	0.137	0	0	0.147	0.17
rs13161	chr6:26222681	52.6126		0	0	0.263	0.265	0.013	0.049	0.197	0.125	0	0	0.135	0.178
rs198809	chr6:26236745	52.6229		0	0	0.263	0.265	0.013	0.049	0.196	0.125	0	0	0.135	0.178
rs9379827	chr6:26261314	52.6407		0	0	0.262	0.264	0.012	0.049	0.195	0.124	0	0	0.134	0.177
rs9295730	chr6:27236785	53.014		0	0	0.239	0.249	0.011	0.054	0.17	0.11	0	0	0.12	0.17
rs451774	chr6:28610529	53.0848	GPX5	0	0	0.234	0.244	0.01	0.057	0.168	0.108	0	0	0.118	0.167
rs377392	chr6:28892720	53.097		0	0	0.233	0.243	0.01	0.057	0.168	0.108	0	0	0.118	0.167
rs429369	chr6:28959887	53.0994		0	0	0.233	0.243	0.01	0.057	0.168	0.108	0	0	0.118	0.167
rs209122	chr6:28983481	53.1002	TRIM27	0	0	0.233	0.243	0.01	0.057	0.168	0.108	0	0	0.118	0.167
rs1264451	chr6:30649216	53.1576	ABCF1	0	0	0.229	0.239	0.009	0.059	0.167	0.107	0	0	0.117	0.165
rs485502	chr6:33051323	54.838	BRD2	0	0	0.136	0.163	0	0.146	0.125	0.073	0	0.043	0.083	0.132
rs11908	chr6:33052724	54.8394	BRD2	0	0	0.136	0.163	0	0.146	0.125	0.073	0	0.043	0.083	0.132
rs1003979	chr6:33222149	55.0077		0	0	0.13	0.159	0	0.157	0.12	0.07	0	0.052	0.08	0.13
rs2495990	chr6:34068589	55.8353		0	0	0.08	0.102	0.001	0.161	0.07	0.037	0	0.123	0.047	0.08
rs6457796	chr6:34936531	56.5652	UHRF1BP1	0	0	0.047	0.056	0.003	0.156	0.049	0.024	0	0.13	0.029	0.047
rs2395626	chr6:35530732	57.005	FANCE	0	0	0.03	0.03	0.005	0.153	0.04	0.02	0	0.125	0.02	0.03
rs1016146	chr6:35553494	57.025	TEAD3	0	0	0.03	0.03	0.005	0.155	0.041	0.021	0	0.127	0.022	0.032
rs2213661	chr6:36234628	57.7339		0	0	0.037	0.045	0.012	0.228	0.084	0.042	0.001	0.169	0.071	0.089
rs1046279	chr6:37040549	58.7581	PI16	0	0.003	0.04	0.042	0.004	0.3	0.13	0.08	0.009	0.219	0.166	0.178
rs804859	chr6:37722440	59.6392	MDGA1	0	0.007	0.034	0.034	0	0.333	0.127	0.09	0.019	0.27	0.209	0.2
rs910516	chr6:38672926	60.5408	BTBD9	0	0.012	0.03	0.03	0	0.342	0.093	0.068	0.014	0.31	0.188	0.168
rs1738240	chr6:38871711	60.7503	DNAH8	0	0.014	0.03	0.03	0	0.342	0.082	0.06	0.01	0.318	0.175	0.155
rs1885615	chr6:39446413	61.5528	KIF6	0	0.018	0.03	0.036	0	0.338	0.053	0.039	0.003	0.312	0.143	0.112
rs9471302	chr6:40395461	63.3332		0	0.026	0.053	0.063	0	0.331	0.053	0.04	0	0.15	0.147	0.097
rs736794	chr6:41105811	64.817	UNC5CL	0	0.035	0.068	0.086	0	0.309	0.068	0.048	0	0.017	0.124	0.082
rs629832	chr6:41394231	65.4624		0	0.075	0.093	0.122	0	0.36	0.093	0.078	0	0.013	0.143	0.112
rs1011101	chr6:41751364	66.2257		0	0.129	0.122	0.162	0	0.432	0.122	0.112	0	0.046	0.175	0.157
rs722269	chr6:42302894	67.3295	TRERF1	0	0.196	0.123	0.163	0	0.507	0.123	0.117	0	0.191	0.19	0.177
rs1537638	chr6:43204177	69.1166	PTK7	0	0.393	0.1	0.139	0	0.733	0.09	0.089	0	0.524	0.177	0.169
rs1563788	chr6:43416341	69.6599	ZNF318	0	0.401	0.1	0.133	0	0.763	0.09	0.083	0	0.558	0.16	0.163
rs945131	chr6:43823972	70.7403		0	0.38	0.078	0.115	0	0.761	0.075	0.073	0	0.543	0.12	0.13
rs3734693	chr6:44073143	71.3379		0	0.387	0.073	0.12	0	0.675	0.08	0.09	0	0.474	0.11	0.13
rs4714772	chr6:44315095	71.8931		0	0.414	0.079	0.137	0	0.546	0.097	0.124	0	0.381	0.11	0.147
rs1322669	chr6:44587154	72.5124		0	0.429	0.085	0.155	0	0.523	0.12	0.15	0.005	0.426	0.125	0.165
rs227850	chr6:44807046	73.0027		0	0.439	0.09	0.17	0	0.524	0.14	0.17	0.01	0.485	0.14	0.18
rs1293457	chr6:44866076	73.1315		0	0.431	0.085	0.162	0	0.513	0.133	0.165	0.009	0.479	0.129	0.169
rs3778507	chr6:45004781	73.4728	SUPT3H	0	0.409	0.071	0.142	0	0.484	0.116	0.151	0.005	0.465	0.102	0.142
rs1284999	chr6:45202417	73.9552	SUPT3H	0	0.378	0.052	0.113	0	0.444	0.092	0.132	0	0.444	0.064	0.104
rs1928533	chr6:45617802	74.6359	RUNX2	0	0.377	0.025	0.065	0	0.466	0.052	0.085	0	0.414	0.022	0.049
rs995564	chr6:46190769	75.384		0	0.391	0.006	0.028	0	0.509	0.018	0.048	0	0.423	0	0.012
rs716493	chr6:46415901	75.6182	RCAN2	0	0.399	0.004	0.021	0	0.527	0.011	0.041	0	0.438	0	0.008
rs1372567	chr6:46437363	75.6405	RCAN2	0	0.4	0.004	0.021	0	0.528	0.011	0.041	0	0.44	0	0.007
rs953887	chr6:46470037	75.6745	RCAN2	0	0.401	0.003	0.02	0	0.531	0.01	0.04	0	0.442	0	0.007
rs993612	chr6:47351757	76.4022	TNFRSF21	0	0.444	0	0.01	0	0.553	0	0.026	0	0.463	0	0.004
rs12525548	chr6:47373800	76.4168	TNFRSF21	0	0.445	0	0.01	0	0.552	0	0.026	0	0.463	0	0.004
rs1556358	chr6:48158258	76.7732		0	0.474	0	0.01	0	0.55	0	0.022	0	0.464	0	0.008
rs2032553	chr6:49240752	76.9489		0	0.488	0	0.01	0	0.549	0	0.021	0	0.464	0	0.009
rs1471539	chr6:49568111	77.003	CENPQ	0	0.491	0	0.01	0	0.548	0	0.02	0	0.463	0	0.01
rs1923523	chr6:50787040	77.3597		0	0.41	-0.007	0.006	0	0.422	0	0.013	0	0.337	-0.004	0.006
rs283548	chr6:51074433	77.4533		0	0.388	-0.009	0.005	0	0.389	0	0.011	0	0.304	-0.005	0.005
rs283545	chr6:51075931	77.454		0	0.388	-0.009	0.005	0	0.389	0	0.011	0	0.303	-0.005	0.005
rs966707	chr6:51736178	77.8834	PKHD1	0	0.29	-0.018	0.001	0	0.237	0	0.002	0	0.151	-0.009	0.001
rs875142	chr6:52336184	78.535	PAQR8	0	0.259	-0.036	-0.005	0	0.164	-0.011	0	0.001	0.062	-0.015	-0.005
rs1542896	chr6:55261386	82.2307		0	0.041	-0.257	-0.18	0	0.001	-0.082	-0.087	0.065	0	-0.027	-0.086
rs1925165	chr6:56096478	82.9	COL21A1	0	0.01	-0.364	-0.267	0	0	-0.089	-0.107	0.038	0	-0.047	-0.133
rs2038149	chr6:56152537	82.9417	COL21A1	0	0.009	-0.371	-0.272	0	0	-0.089	-0.108	0.036	0	-0.048	-0.136
rs1925152	chr6:56210668	82.9849	COL21A1	0	0.007	-0.378	-0.278	0	0	-0.09	-0.11	0.035	0	-0.05	-0.139
rs1925154	chr6:56212481	82.9862	COL21A1	0	0.007	-0.378	-0.278	0	0	-0.09	-0.11	0.035	0	-0.05	-0.139
rs2599697	chr6:56907221	83.4476		0	0.003	-0.416	-0.311	0	0	-0.094	-0.11	0.036	0	-0.046	-0.136
rs3908886	chr6:58136566	83.9586		0	0	-0.457	-0.347	0	0	-0.1	-0.11	0.038	0	-0.04	-0.13
rs12197273	chr6:62030461	84.1741		0	0.002	-0.462	-0.352	0	0	-0.105	-0.115	0.035	0	-0.049	-0.139
rs9378077	chr6:62078359	84.177		0	0.002	-0.462	-0.352	0	0	-0.105	-0.115	0.035	0	-0.049	-0.139
rs977382	chr6:62118323	84.1795		0	0.002	-0.462	-0.352	0	0	-0.105	-0.115	0.035	0	-0.049	-0.139
rs1040802	chr6:63530401	84.266		0	0.002	-0.463	-0.353	0	0	-0.108	-0.118	0.034	0	-0.053	-0.143
rs1630182	chr6:64266171	84.4075		0	0.004	-0.464	-0.354	0	0	-0.112	-0.122	0.032	0	-0.06	-0.15
rs1922964	chr6:65020814	84.6738	EYS	0	0.006	-0.467	-0.357	0	0	-0.12	-0.13	0.028	0	-0.074	-0.164
rs1418903	chr6:68326677	86.6077		0	0.056	-0.422	-0.334	0	0	-0.078	-0.088	0.02	0	-0.064	-0.16
rs1016461	chr6:69092970	86.9887		0	0.065	-0.41	-0.33	0	0	-0.07	-0.08	0.022	0	-0.06	-0.16
rs2210867	chr6:69802775	87.3615	BAI3	0	0.054	-0.41	-0.33	0	0	-0.063	-0.076	0.026	0	-0.06	-0.16
rs1817255	chr6:70362620	87.7669		0	0.041	-0.41	-0.33	0	0	-0.055	-0.072	0.03	0	-0.06	-0.16
rs6910674	chr6:71779542	88.9981		0	0.017	-0.3	-0.23	0	0.002	0	-0.01	0.077	0	-0.01	-0.08
rs199630	chr6:72309781	89.4948		0	0.016	-0.231	-0.171	0	0.002	0	-0.005	0.097	0	-0.005	-0.05
rs1321834	chr6:72454519	89.6317		0	0.016	-0.212	-0.154	0	0.002	0	-0.004	0.102	0	-0.004	-0.042
rs1969530	chr6:72917997	90.0622	RIMS1	0	0.015	-0.156	-0.106	0	0.002	0.002	0.001	0.117	0	0.002	-0.019
rs1416546	chr6:73178627	90.3133		0	0.017	-0.138	-0.091	0	0.001	0.009	0.006	0.115	0	0.009	-0.014
rs1935515	chr6:73592480	90.703	KCNQ5	0	0.02	-0.111	-0.068	0	0.001	0.021	0.014	0.113	0	0.021	-0.006
rs2000203	chr6:73753787	90.843	KCNQ5	0	0.021	-0.101	-0.059	0	0	0.025	0.017	0.113	0	0.025	-0.003
rs2796051	chr6:73902596	90.972	KCNQ5 KCNQ5-AS1	0	0.022	-0.092	-0.052	0	0	0.029	0.019	0.112	0	0.029	-0.001
rs1370436	chr6:74581135	91.4505	CD109	0	0.032	-0.085	-0.05	0	0.002	0.035	0.025	0.065	0	0.021	0
rs675497	chr6:75114270	91.7884		0	0.039	-0.082	-0.05	0	0.004	0.038	0.028	0.03	0	0.014	0
rs508557	chr6:75374741	91.9428		0	0.043	-0.081	-0.05	0	0.005	0.039	0.029	0.014	0	0.011	0
rs2998367	chr6:76228233	92.3261	FILIP1	0	0.042	-0.08	-0.05	0	0.007	0.04	0.03	0.005	0	0.007	0
rs12606	chr6:76681461	92.4758	MYO6	0	0.041	-0.08	-0.05	0	0.008	0.04	0.03	0.004	0	0.005	0
rs1486039	chr6:76965256	92.599		0	0.04	-0.08	-0.05	0	0.009	0.04	0.03	0.003	0	0.004	0
rs6907703	chr6:77235069	92.7145		0	0.04	-0.08	-0.05	0	0.01	0.04	0.03	0.002	0	0.003	0
rs9352376	chr6:77471874	92.8345		0	0.039	-0.08	-0.05	0	0.011	0.04	0.03	0.001	0	0.002	0
rs1462476	chr6:77572235	92.8857		0	0.039	-0.08	-0.05	0	0.011	0.04	0.03	0.001	0	0.001	0
rs1398576	chr6:78581577	93.4881		0	0.067	-0.041	-0.026	0	0.032	0.079	0.069	0	0	0.015	0.005
rs1567095	chr6:79390707	93.9832		0	0.096	-0.001	-0.001	0	0.052	0.119	0.109	0	0	0.029	0.01
rs2063123	chr6:79715254	94.146	PHIP	0	0.108	0.009	0.009	0	0.055	0.133	0.12	0	0	0.037	0.016
rs1537740	chr6:80035233	94.2794		0	0.117	0.017	0.017	0	0.057	0.145	0.13	0	0	0.044	0.021
rs932492	chr6:80531291	94.4914		0	0.133	0.029	0.029	0	0.059	0.164	0.144	0	0	0.055	0.03
rs239558	chr6:80777764	94.5785	TTK	0	0.139	0.035	0.035	0	0.061	0.172	0.15	0	0	0.059	0.033
rs1040596	chr6:81097021	94.6576	BCKDHB	0	0.145	0.039	0.039	0	0.062	0.179	0.156	0	0	0.063	0.036
rs1436876	chr6:81285246	94.722		0	0.15	0.043	0.043	0	0.062	0.185	0.161	0	0	0.066	0.039
rs533393	chr6:81706363	94.8802		0	0.161	0.053	0.053	0	0.064	0.199	0.172	0	0	0.074	0.045
rs310389	chr6:81834636	94.9357		0	0.165	0.056	0.056	0	0.065	0.204	0.175	0	0	0.077	0.047
rs6454240	chr6:82555476	95.2552		0	0.167	0.068	0.07	0	0.064	0.182	0.16	0	0.003	0.065	0.04
rs885582	chr6:82668916	95.3334		0	0.166	0.07	0.073	0	0.064	0.173	0.153	0	0.003	0.06	0.037
rs770906	chr6:83140060	95.6718		0	0.162	0.08	0.087	0	0.061	0.136	0.126	0	0.007	0.04	0.023
rs4111785	chr6:83537185	95.9595		0	0.158	0.089	0.098	0	0.059	0.104	0.103	0	0.01	0.022	0.012
rs983087	chr6:84010983	96.2899	ME1	0	0.201	0.102	0.117	0	0.082	0.117	0.123	0	0.034	0.023	0.013
rs2296412	chr6:84625643	96.597		0	0.246	0.114	0.136	0	0.106	0.136	0.148	0	0.06	0.026	0.016
rs2025427	chr6:85009859	96.7207		0	0.264	0.119	0.143	0	0.115	0.143	0.158	0	0.07	0.027	0.017
rs1887504	chr6:85473926	96.8364		0	0.281	0.123	0.15	0	0.124	0.15	0.167	0	0.079	0.028	0.018
rs946296	chr6:87364428	97.006		0	0.305	0.13	0.16	0	0.137	0.16	0.18	0	0.093	0.03	0.02
rs513640	chr6:87532681	97.0731		0	0.301	0.133	0.162	0	0.132	0.161	0.18	0	0.089	0.03	0.019
rs910563	chr6:88115604	97.3961	C6orf163	0.001	0.284	0.146	0.172	0	0.108	0.168	0.18	0	0.07	0.03	0.016
rs6940716	chr6:88199698	97.4378	C6orf165	0.001	0.281	0.148	0.173	0	0.105	0.169	0.18	0	0.068	0.03	0.016
rs1051131	chr6:88278265	97.4903	SLC35A1	0.001	0.279	0.15	0.175	0	0.101	0.17	0.18	0	0.065	0.03	0.015
rs632385	chr6:88728660	97.861		0.003	0.259	0.164	0.186	0	0.073	0.177	0.18	0	0.044	0.03	0.011
rs1884831	chr6:88951853	98.0945		0.004	0.247	0.174	0.194	0	0.062	0.18	0.178	0	0.035	0.03	0.01
rs2246529	chr6:89341458	98.5757		0.007	0.224	0.193	0.213	0	0.055	0.18	0.168	0	0.031	0.03	0.01
rs1040676	chr6:89577866	98.8855	RNGTT	0.009	0.209	0.205	0.225	0	0.051	0.18	0.162	0	0.029	0.03	0.01
rs205224	chr6:89800118	99.2257		0.01	0.188	0.205	0.232	0	0.043	0.175	0.158	0	0.023	0.03	0.012
rs1980986	chr6:89818726	99.2548		0.01	0.186	0.205	0.233	0	0.043	0.175	0.157	0	0.023	0.03	0.013
rs7773548	chr6:89877196	99.3528	SRSF12	0.01	0.179	0.203	0.234	0	0.04	0.173	0.156	0	0.021	0.03	0.014
rs1179900	chr6:90377879	100.2087	ANKRD6	0.012	0.117	0.194	0.248	0	0.019	0.154	0.148	0	0.006	0.028	0.018
rs1055403	chr6:90695684	100.7907	BACH2	0.017	0.075	0.206	0.272	0	0.005	0.136	0.142	0	0.002	0.022	0.012
rs285619	chr6:91110916	101.5663		0.048	0.062	0.295	0.382	0	0	0.124	0.151	0	0	0.026	0.016
rs790605	chr6:91162617	101.6699		0.054	0.062	0.31	0.401	0	0	0.123	0.153	0	0	0.027	0.017
rs1145739	chr6:91466661	102.2316		0.081	0.05	0.374	0.483	0	0	0.12	0.165	0	0	0.037	0.029
rs1145773	chr6:91633274	102.4978		0.093	0.034	0.39	0.51	0	0	0.12	0.17	0	0	0.045	0.04
rs1884260	chr6:92044752	103.1008		0.119	0.01	0.437	0.583	0	0	0.124	0.187	0	0	0.066	0.067
rs2144363	chr6:92098625	103.1756		0.122	0.013	0.45	0.6	0	0	0.127	0.192	0	0	0.071	0.072
rs1979797	chr6:92549591	103.7172		0.143	0.039	0.542	0.725	0	0	0.149	0.23	0	0	0.103	0.11
rs1391503	chr6:92596733	103.764		0.145	0.042	0.55	0.736	0	0	0.151	0.233	0	0	0.106	0.113
rs1498252	chr6:92706956	103.8701		0.149	0.047	0.568	0.76	0	0	0.155	0.241	0	0	0.112	0.121
rs1373376	chr6:92947386	104.0615		0.163	0.053	0.605	0.807	0	0	0.167	0.259	0	0	0.122	0.134
rs1863659	chr6:93224101	104.2454		0.189	0.052	0.651	0.859	0	0	0.187	0.284	0	0.001	0.127	0.145
rs1427123	chr6:93288722	104.2844		0.195	0.052	0.661	0.87	0	0.001	0.191	0.29	0	0.001	0.129	0.147
rs1040155	chr6:93617871	104.5006		0.226	0.051	0.715	0.93	0	0.001	0.215	0.32	0	0.002	0.135	0.16
rs1338248	chr6:93639259	104.5143		0.228	0.051	0.719	0.934	0	0.001	0.217	0.322	0	0.002	0.135	0.161
rs1324103	chr6:93957737	104.7035		0.255	0.05	0.766	0.987	0	0.001	0.237	0.348	0	0.002	0.141	0.172
rs1548297	chr6:94039775	104.761	EPHA7	0.264	0.05	0.78	1.003	0	0.002	0.244	0.357	0	0.002	0.143	0.176
rs491112	chr6:94226368	104.8957		0.283	0.049	0.814	1.041	0	0.002	0.259	0.375	0	0.003	0.147	0.184
rs1488318	chr6:94740324	105.2567		0.265	0.036	0.801	1.044	0	0.001	0.231	0.357	0	0.002	0.14	0.182
rs4302647	chr6:94822978	105.3111		0.258	0.034	0.793	1.039	0	0.001	0.223	0.35	0	0.002	0.138	0.181
rs952577	chr6:95044774	105.4442		0.242	0.027	0.773	1.026	0	0.001	0.203	0.332	0	0.002	0.132	0.177
rs2493964	chr6:95428655	105.6637		0.214	0.016	0.74	1.004	0	0.001	0.17	0.304	0	0.001	0.123	0.17
rs169125	chr6:95623707	105.7465		0.203	0.012	0.728	0.995	0	0.001	0.158	0.293	0	0.001	0.12	0.168
rs2890370	chr6:95942917	105.8717		0.187	0.006	0.709	0.983	0	0	0.139	0.277	0	0	0.115	0.164
rs4839952	chr6:96231014	105.9916		0.172	0	0.691	0.971	0	0	0.121	0.261	0	0	0.11	0.16
rs716192	chr6:96618410	106.1683	FUT9	0.162	0	0.717	1.024	0	0	0.125	0.272	0	0	0.115	0.18
rs7772067	chr6:96676626	106.1953	FUT9	0.16	0	0.721	1.032	0	0	0.126	0.274	0	0	0.116	0.183
rs2472922	chr6:96941692	106.346		0.152	0.001	0.745	1.081	0	0	0.13	0.284	0	0	0.12	0.202
rs538052	chr6:97265944	106.5199		0.142	0.001	0.773	1.136	0	0	0.136	0.296	0	0.001	0.126	0.222
rs2095348	chr6:97268725	106.5216		0.142	0.001	0.773	1.137	0	0	0.136	0.297	0	0.001	0.126	0.223
rs1014976	chr6:97735163	106.8505	MMS22L	0.124	0.002	0.826	1.242	0	0	0.146	0.32	0	0.001	0.136	0.262
rs6569342	chr6:98720556	107.6043		0.127	0.015	0.965	1.465	0	0	0.18	0.403	0	0.003	0.182	0.353
rs210400	chr6:99037999	107.8591		0.131	0.021	1.013	1.539	0	0	0.193	0.433	0	0.004	0.2	0.383
rs1997936	chr6:99542724	108.2137		0.135	0.045	1.076	1.608	0	0.004	0.221	0.48	0	0.023	0.225	0.419
rs7776325	chr6:99971685	108.51	PNISR	0.138	0.075	1.127	1.646	0	0.01	0.251	0.521	0	0.048	0.246	0.446
rs2894891	chr6:100316628	108.7463		0.139	0.099	1.167	1.677	0	0.014	0.275	0.554	0	0.068	0.262	0.467
rs761713	chr6:100716059	109.0446		0.14	0.125	1.209	1.707	0	0.02	0.3	0.591	0	0.091	0.282	0.493
rs761711	chr6:100732869	109.0576		0.139	0.125	1.209	1.706	0	0.02	0.299	0.591	0	0.091	0.282	0.494
rs240153	chr6:101173856	109.431	ASCC3	0.128	0.132	1.201	1.68	0	0.03	0.296	0.599	0	0.104	0.297	0.52
rs239229	chr6:101212696	109.461	ASCC3	0.127	0.132	1.201	1.678	0	0.031	0.295	0.599	0	0.105	0.298	0.522
rs239189	chr6:101235508	109.4787	ASCC3	0.127	0.133	1.2	1.676	0	0.031	0.295	0.6	0	0.106	0.299	0.524
rs846773	chr6:101397983	109.6105	ASCC3	0.123	0.135	1.198	1.667	0	0.035	0.294	0.602	0	0.11	0.304	0.533
rs2207958	chr6:102093782	110.1998	GRIK2	0.112	0.161	1.236	1.704	0	0.068	0.312	0.644	0	0.152	0.354	0.604
rs1953817	chr6:103155305	110.9363		0.118	0.23	1.405	1.94	0	0.151	0.393	0.769	0	0.255	0.479	0.766
rs500204	chr6:103732117	111.2472		0.115	0.26	1.447	2.002	0	0.204	0.407	0.785	0.004	0.294	0.488	0.77
rs1155126	chr6:103908333	111.3296		0.113	0.269	1.456	2.016	0	0.22	0.41	0.787	0.005	0.304	0.487	0.767
rs6929015	chr6:104215377	111.4942		0.111	0.285	1.474	2.044	0	0.251	0.415	0.79	0.007	0.324	0.485	0.76
rs860933	chr6:104609135	111.7276		0.108	0.308	1.5	2.084	0	0.295	0.422	0.795	0.011	0.352	0.483	0.751
rs880177	chr6:105957405	113.2977	PREP	0.112	0.302	1.535	2.104	0	0.553	0.48	0.811	0.022	0.324	0.474	0.665
rs9386461	chr6:106176614	113.699		0.113	0.276	1.515	2.056	0	0.599	0.48	0.799	0.019	0.318	0.466	0.645
rs1475270	chr6:106794072	114.7539	ATG5	0.175	0.228	1.651	2.141	0	0.798	0.57	0.88	0.031	0.296	0.52	0.698
rs1665914	chr6:107436099	115.9986		0.271	0.125	1.79	2.2	0.003	1.001	0.74	1.03	0.088	0.285	0.64	0.78
rs2050042	chr6:108415352	117.4728		0.515	0.141	2.302	2.648	0.033	1.131	0.911	1.186	0.228	0.278	0.889	1.058
rs217532	chr6:108628006	117.6909		0.561	0.145	2.409	2.744	0.04	1.139	0.944	1.217	0.257	0.293	0.939	1.117
rs1260658	chr6:109526918	118.5153	CEP57L1	0.753	0.174	2.869	3.143	0.073	1.121	1.129	1.384	0.366	0.378	1.159	1.349
rs351755	chr6:109644766	118.6215		0.779	0.179	2.933	3.197	0.078	1.115	1.158	1.409	0.38	0.391	1.19	1.38
rs736830	chr6:109819992	118.7501	PPIL6	0.811	0.185	3.01	3.263	0.084	1.107	1.193	1.44	0.398	0.406	1.228	1.418
rs1046943	chr6:109890634	118.7993	ZBTB24	0.823	0.188	3.04	3.288	0.086	1.104	1.206	1.452	0.404	0.412	1.242	1.432
rs781499	chr6:111367616	120.0081		0.693	0.149	2.748	2.917	0.037	0.913	0.949	1.178	0.258	0.218	1.029	1.229
rs1022092	chr6:111533979	120.1879	SLC16A10	0.672	0.144	2.694	2.854	0.035	0.908	0.922	1.141	0.252	0.216	1.015	1.206
rs1158747	chr6:112607343	121.2568	LAMA4	0.587	0.144	2.463	2.573	0.023	0.868	0.785	0.952	0.226	0.2	0.955	1.108
rs1565528	chr6:113776568	122.1586		0.599	0.198	2.494	2.578	0.017	0.809	0.743	0.911	0.212	0.196	0.97	1.132
rs1491074	chr6:113790603	122.1672		0.598	0.198	2.493	2.578	0.017	0.808	0.743	0.912	0.211	0.197	0.97	1.132
rs1033391	chr6:113866756	122.2143		0.591	0.198	2.491	2.578	0.017	0.807	0.744	0.915	0.209	0.2	0.97	1.132
rs773676	chr6:114155885	122.3678		0.57	0.197	2.485	2.576	0.015	0.803	0.747	0.926	0.202	0.211	0.97	1.134
rs2030926	chr6:114173820	122.3782		0.569	0.197	2.485	2.576	0.015	0.802	0.748	0.926	0.201	0.211	0.97	1.134
rs963884	chr6:114236941	122.4133		0.564	0.197	2.483	2.576	0.014	0.801	0.748	0.929	0.2	0.214	0.97	1.134
rs548388	chr6:114342082	122.4695	FLJ34503	0.556	0.196	2.481	2.575	0.014	0.8	0.749	0.933	0.197	0.218	0.97	1.135
rs1415428	chr6:114798204	122.7042		0.524	0.195	2.472	2.573	0.011	0.793	0.754	0.949	0.186	0.234	0.97	1.137
rs7759765	chr6:115886352	123.1251		0.452	0.185	2.437	2.552	0.007	0.768	0.761	0.969	0.163	0.256	0.959	1.132
rs1041883	chr6:116796071	123.5852	DSE	0.34	0.156	2.355	2.488	0.003	0.705	0.766	0.964	0.132	0.259	0.917	1.105
rs9398436	chr6:116920626	123.6566		0.323	0.152	2.342	2.478	0.003	0.695	0.767	0.963	0.127	0.26	0.911	1.101
rs544047	chr6:117715011	124.0224		0.232	0.126	2.214	2.359	0	0.629	0.748	0.932	0.101	0.254	0.854	1.049
rs1321807	chr6:117791685	124.0523	ROS1	0.224	0.122	2.14	2.281	0	0.608	0.723	0.901	0.098	0.246	0.826	1.014
rs2243379	chr6:117831155	124.0666	ROS1	0.222	0.122	2.134	2.275	0	0.606	0.72	0.899	0.099	0.245	0.827	1.015
rs1407184	chr6:117840410	124.0706	ROS1	0.221	0.122	2.132	2.274	0	0.606	0.719	0.898	0.099	0.245	0.827	1.015
rs1321813	chr6:117934984	124.1125	DCBLD1	0.213	0.121	2.114	2.259	0	0.6	0.712	0.891	0.101	0.242	0.83	1.017
rs210617	chr6:117966751	124.1262	DCBLD1	0.21	0.121	2.108	2.253	0	0.598	0.709	0.889	0.102	0.241	0.831	1.018
rs1541317	chr6:118130009	124.192	NUS1	0.197	0.12	2.08	2.229	0	0.59	0.697	0.879	0.106	0.237	0.835	1.022
rs1012509	chr6:119549906	124.6547	MAN1A1	0.107	0.112	1.879	2.058	0	0.528	0.613	0.805	0.135	0.206	0.867	1.049
rs7758258	chr6:119874817	124.7713		0.084	0.11	1.829	2.015	0	0.512	0.592	0.786	0.143	0.198	0.875	1.056
rs937091	chr6:120236615	124.9195		0.056	0.107	1.765	1.96	0	0.493	0.565	0.763	0.152	0.188	0.885	1.065
rs763075	chr6:122253219	125.8205		0.036	0.117	1.714	1.963	0	0.5	0.525	0.75	0.148	0.373	0.915	1.119
rs1563512	chr6:122521445	125.9573		0.035	0.119	1.711	1.968	0	0.503	0.521	0.75	0.146	0.404	0.919	1.127
rs873460	chr6:123766181	127.1018	TRDN	0.101	0.137	1.795	2.103	0.004	0.413	0.721	0.938	0.461	0.585	1.221	1.328
rs1321084	chr6:123944240	127.3646	TRDN	0.112	0.152	1.835	2.137	0.013	0.418	0.777	0.986	0.486	0.607	1.277	1.376
rs941815	chr6:123962271	127.3915	TRDN	0.113	0.154	1.839	2.141	0.014	0.418	0.782	0.99	0.488	0.609	1.282	1.38
rs1407529	chr6:124726881	128.8947	NKAIN2	0.139	0.219	1.975	2.265	0.051	0.475	1.053	1.27	0.487	0.695	1.526	1.66
rs659491	chr6:124870435	129.2082	NKAIN2	0.12	0.202	1.918	2.208	0.046	0.439	1.053	1.292	0.444	0.68	1.503	1.67
rs781739	chr6:125274032	130.0627	STL	0.046	0.126	1.684	1.976	0.019	0.28	0.992	1.308	0.301	0.602	1.352	1.629
rs911966	chr6:125433792	130.3372	RNF217	0.045	0.139	1.7	2.004	0.015	0.264	1	1.34	0.263	0.575	1.32	1.623
rs524394	chr6:125573809	130.5615	TPD52L1	0.045	0.15	1.714	2.026	0.012	0.251	1.007	1.367	0.233	0.553	1.293	1.619
rs1569741	chr6:126425169	131.5907		0.041	0.237	1.758	2.111	0.003	0.37	1.02	1.426	0.128	0.532	1.216	1.61
rs1340952	chr6:126993203	131.9546		0.039	0.277	1.769	2.137	0.001	0.459	1.02	1.43	0.1	0.545	1.202	1.61
rs1538956	chr6:127005719	131.9579		0.039	0.277	1.769	2.137	0.001	0.46	1.02	1.43	0.099	0.545	1.202	1.61
rs1022573	chr6:127096607	131.982		0.039	0.28	1.769	2.139	0.001	0.466	1.02	1.43	0.097	0.546	1.201	1.61
rs1543432	chr6:127739711	132.1338		0.039	0.319	1.782	2.155	0.001	0.519	1.023	1.433	0.095	0.614	1.207	1.622
rs482607	chr6:129027553	132.8308		0.037	0.513	1.845	2.231	0	0.773	1.037	1.447	0.089	0.963	1.242	1.685
rs1894641	chr6:130062643	133.8697	ARHGAP18	0.052	0.751	1.956	2.337	0	0.887	0.936	1.337	0.05	1.223	1.163	1.622
rs2007339	chr6:131387357	135.2013	EPB41L2	0.084	1.098	1.758	2.068	0	1.071	0.662	1	0.005	1.455	0.886	1.346
rs942150	chr6:131744986	135.543		0.081	1.128	1.669	1.979	0	1.07	0.597	0.931	0.003	1.506	0.828	1.305
rs1033540	chr6:131778995	135.5665		0.081	1.13	1.663	1.973	0	1.07	0.592	0.927	0.003	1.509	0.824	1.302
rs1830971	chr6:132190046	135.9845	ENPP1	0.077	1.168	1.554	1.864	0	1.07	0.513	0.843	0	1.572	0.753	1.252
rs48385	chr6:133353042	137.1718		0.074	1.129	1.483	1.668	0	0.958	0.433	0.718	0	1.567	0.553	1.033
rs969282	chr6:134246785	138.5069		0.056	1.224	1.309	1.474	0	0.953	0.37	0.63	0	1.489	0.369	0.849
rs229919	chr6:134271012	138.5471		0.055	1.228	1.302	1.467	0	0.953	0.367	0.627	0	1.488	0.365	0.845
rs162192	chr6:134308392	138.6059		0.054	1.234	1.291	1.457	0	0.955	0.364	0.624	0	1.487	0.359	0.839
rs1981093	chr6:134622709	139.093	SGK1	0.044	1.274	1.213	1.385	0	0.965	0.336	0.598	0	1.498	0.322	0.809
rs1041480	chr6:135414769	140.1656	HBS1L	0.035	1.269	1.147	1.333	0	0.973	0.295	0.57	0	1.691	0.345	0.91
rs2064430	chr6:135684449	140.5318	AHI1	0.042	1.265	1.139	1.319	0	0.957	0.284	0.548	0	1.732	0.356	0.932
rs7765567	chr6:136438567	141.5137	PDE7B	0.082	1.267	1.161	1.305	0	0.913	0.275	0.51	0	1.777	0.38	0.95
rs1028331	chr6:136718671	141.9598	MAP7	0.11	1.274	1.188	1.31	0	0.894	0.28	0.501	0	1.771	0.389	0.941
rs1570056	chr6:137101620	142.594	MAP3K5	0.16	1.305	1.226	1.334	0	0.884	0.292	0.5	0	1.748	0.396	0.946
rs2040034	chr6:137337027	143.0077		0.193	1.324	1.249	1.349	0	0.879	0.3	0.499	0	1.734	0.4	0.95
rs999638	chr6:138112980	144.7953		0.37	1.18	1.037	1.119	0	0.813	0.2	0.326	0	1.905	0.418	0.896
rs1018513	chr6:139215469	147.3189	ECT2L	0.384	1.371	0.797	0.841	0	0.985	0.157	0.264	0	2.229	0.493	0.996
rs1358716	chr6:139487697	147.8132		0.344	1.448	0.777	0.811	0	1.07	0.152	0.254	0	2.324	0.498	1.006
rs2032017	chr6:140069602	148.6908		0.273	1.502	0.708	0.731	0	1.226	0.15	0.257	0	2.441	0.445	0.934
rs1977739	chr6:140305520	148.9571		0.251	1.511	0.684	0.704	0	1.273	0.15	0.26	0	2.472	0.423	0.905
rs2027195	chr6:140992696	149.4309		0.247	1.422	0.641	0.648	0	1.331	0.167	0.282	0	2.687	0.442	0.909
rs647875	chr6:141179444	149.5261		0.247	1.401	0.633	0.637	0	1.342	0.171	0.286	0	2.734	0.446	0.911
rs1349710	chr6:141536371	149.6186		0.247	1.382	0.624	0.626	0	1.353	0.175	0.291	0	2.779	0.451	0.912
rs225604	chr6:142494259	149.8412		0.246	1.335	0.604	0.599	0	1.379	0.184	0.302	0	2.888	0.462	0.917
rs1931992	chr6:142642900	149.9063		0.246	1.321	0.598	0.591	0	1.386	0.186	0.305	0	2.919	0.465	0.918
rs839556	chr6:142913571	150.0853	LOC153910	0.256	1.268	0.585	0.573	0	1.399	0.191	0.307	0	2.937	0.466	0.911
rs200148	chr6:143387389	150.4696	LOC100507489	0.3	1.118	0.562	0.542	0	1.41	0.195	0.296	0	2.81	0.447	0.868
rs583341	chr6:144642663	151.6919		0.471	0.816	0.565	0.514	0.001	1.403	0.221	0.287	0.008	2.48	0.427	0.775
rs1832378	chr6:145733157	152.4646		0.466	0.567	0.473	0.427	0.003	1.079	0.174	0.225	0.015	2.02	0.365	0.658
rs2025157	chr6:146851348	152.7424		0.433	0.444	0.409	0.372	0.005	0.892	0.141	0.186	0.017	1.786	0.326	0.597
rs730862	chr6:148007185	153.7975		0.238	0.104	0.23	0.208	0.025	0.359	0.054	0.078	0.004	0.999	0.186	0.404
rs1572856	chr6:148485529	154.7073		0.197	0.03	0.179	0.159	0.019	0.164	0.019	0.032	0	0.668	0.118	0.313
rs6570858	chr6:148867641	155.6306	SASH1	0.202	0.012	0.132	0.112	0.01	0.067	0.004	0.007	0	0.469	0.081	0.252
rs6570867	chr6:148972548	155.896		0.204	0.007	0.116	0.096	0.008	0.044	0.001	0.002	0	0.417	0.073	0.236
rs4131485	chr6:149041429	156.0776		0.206	0.006	0.109	0.089	0.007	0.036	-0.001	0	0	0.399	0.069	0.232
rs1934221	chr6:149416298	156.8441	UST	0.213	0.015	0.102	0.082	0.004	0.043	-0.008	0	0	0.417	0.062	0.247
rs237012	chr6:149770891	157.4921	TAB2	0.203	0.045	0.08	0.065	0.004	0.07	-0.01	0	0	0.467	0.055	0.25
rs369643	chr6:149841491	157.5909	ZC3H12D	0.2	0.05	0.076	0.062	0.005	0.075	-0.01	0	0	0.477	0.054	0.25
rs2151913	chr6:150172335	158.0248	PCMT1	0.191	0.073	0.06	0.05	0.006	0.096	-0.01	0	0	0.515	0.05	0.249
rs1389717	chr6:151083493	159.2862	PLEKHG1	0.173	0.052	0.034	0.034	0.032	0.057	-0.007	0	0.001	0.481	0.024	0.196
rs1107523	chr6:151129420	159.383	PLEKHG1	0.173	0.049	0.032	0.032	0.036	0.055	-0.006	0	0.001	0.471	0.022	0.191
rs1771816	chr6:151322270	159.8407	MTHFD1L	0.173	0.034	0.023	0.023	0.054	0.042	-0.002	0	0.002	0.423	0.013	0.168
rs1003027	chr6:151533851	160.373		0.17	0.023	0.016	0.016	0.074	0.027	0	0.004	0.002	0.351	0.006	0.141
rs967726	chr6:151652717	160.6905	AKAP12	0.168	0.019	0.013	0.013	0.086	0.018	0	0.007	0.001	0.304	0.003	0.125
rs10002	chr6:151756798	160.9958		0.166	0.014	0.01	0.01	0.097	0.009	0	0.01	0.001	0.259	0	0.11
rs718527	chr6:152511829	162.6803	SYNE1	0.112	0.043	0.017	0.034	0.011	0.1	0	0.017	0	0.355	0	0.117
rs1407491	chr6:152982685	163.3512	SYNE1	0.092	0.053	0.031	0.058	0.001	0.14	0	0.031	0	0.368	0	0.113
rs317077	chr6:153569834	164.0597		0.073	0.057	0.051	0.091	0	0.172	0.001	0.052	0	0.357	0	0.101
rs790266	chr6:154583595	165.4864	IPCEF1 OPRM1	0.076	0.026	0.07	0.115	0	0.18	0.03	0.099	0	0.29	0	0.11
rs1361218	chr6:154757804	165.8468		0.079	0.018	0.077	0.118	0	0.174	0.037	0.114	0	0.265	0	0.11
rs1385732	chr6:155521917	167.314	TIAM2	0.094	0.004	0.081	0.111	0.001	0.095	0.054	0.121	0	0.173	0	0.107
rs912722	chr6:155623527	167.4845	TFB1M	0.095	0.003	0.075	0.105	0.001	0.073	0.05	0.115	0	0.162	0	0.101
rs231958	chr6:155797096	167.7545	NOX3	0.096	0.002	0.067	0.097	0	0.039	0.045	0.107	0	0.145	0	0.09
rs1902064	chr6:156764082	169.0014		0.085	0	0.03	0.04	0	0	0.03	0.08	0	0.073	0	0.08
rs767860	chr6:157458372	169.7746	ARID1B	0.039	0	0.022	0.025	0	0	0.03	0.072	0	0.016	0	0.065
rs924928	chr6:157859789	170.1873	ZDHHC14	0.021	0	0.018	0.016	0	0	0.032	0.07	0	0.006	0	0.058
rs602890	chr6:157989387	170.2787	ZDHHC14	0.019	0	0.017	0.014	0	0	0.033	0.07	0	0.009	0	0.057
rs1832871	chr6:158642022	170.9088		0.007	0	0.011	0.002	0	0	0.039	0.07	0	0.028	0	0.051
rs1866896	chr6:158860999	171.2509		0.004	0	0.007	0	0	0	0.037	0.067	0	0.034	0	0.05
rs182429	chr6:159389562	172.2645		0	0	0.003	0.003	0	0.003	0.035	0.068	0	0.053	0	0.053
rs923459	chr6:159481840	172.4367		0	0	0.004	0.004	0	0.006	0.039	0.073	0	0.061	0	0.054
rs294882	chr6:159522989	172.5166	FNDC1	0	0	0.005	0.005	0	0.007	0.04	0.075	0	0.064	0	0.055
rs409359	chr6:159864986	173.2153		0	0	0.01	0.01	0	0.014	0.046	0.086	0	0.088	0	0.058
rs2758319	chr6:159989999	173.4184		0	0	0.01	0.01	0	0.015	0.042	0.082	0	0.091	0	0.056
rs927450	chr6:160102086	173.6061	LOC100129518	0	0.001	0.01	0.01	0	0.016	0.038	0.078	0	0.093	0	0.054
rs927451	chr6:160133426	173.6312	MRPL18	0	0.001	0.01	0.01	0	0.016	0.037	0.077	0	0.093	0	0.054
rs675162	chr6:160696315	174.2387	SLC22A3	0	0.001	0.008	0.008	0	0.015	0.025	0.058	0	0.094	0	0.045
rs783182	chr6:161088538	174.5597	PLG	0	0.002	0.004	0.004	0	0.011	0.019	0.042	0	0.091	0	0.039
rs1247555	chr6:161109008	174.5798		0	0.002	0.004	0.004	0	0.01	0.018	0.041	0	0.091	0	0.038
rs1080085	chr6:161632025	175.3165		0	0.001	-0.003	-0.003	0	0.003	0.007	0.014	0	0.07	0	0.027
rs1893098	chr6:162196867	176.3839	PARK2	0	0	-0.014	-0.022	0	0	0	0	0	0.022	0	0.016
rs1954948	chr6:162521711	177.0007	PARK2	0	0	-0.02	-0.04	0	0	0	0	0	0.001	0	0.01
rs1333962	chr6:163188894	178.2774	PACRG	0	0.001	0.003	0	0	0	0.013	0.006	0	0	0.016	0.026
rs942731	chr6:164585475	180.3255		0	0.098	0.037	0.037	0	0	0.05	0.053	0.006	0	0.07	0.06
rs1886672	chr6:164641899	180.3855		0	0.1	0.038	0.038	0	0	0.05	0.054	0.006	0	0.07	0.06
rs727811	chr6:164965324	180.8344		0	0.112	0.047	0.047	0	0.001	0.05	0.058	0.013	0	0.07	0.06
rs646444	chr6:165642335	182.0952	C6orf118	0	0.09	0.061	0.06	0	0.045	0.059	0.06	0.025	0.013	0.083	0.051
rs491253	chr6:165685823	182.1787	PDE10A	0	0.093	0.062	0.06	0	0.054	0.058	0.06	0.024	0.018	0.085	0.052
rs875590	chr6:165989348	182.8575	PDE10A	0	0.11	0.069	0.06	0	0.128	0.051	0.06	0.016	0.056	0.106	0.059
rs3002430	chr6:166210146	183.4839		0	0.135	0.08	0.07	0	0.184	0.055	0.065	0.013	0.087	0.129	0.07
rs1445282	chr6:166445194	184.2702		0	0.146	0.082	0.072	0	0.216	0.049	0.059	0.012	0.117	0.145	0.072
rs880900	chr6:167059469	186.3274	RPS6KA2	0	0.059	0.017	0.017	0	0.12	0	0	0.026	0.131	0.093	0.017
rs533810	chr6:167109679	186.52	RPS6KA2	0	0.048	0.015	0.015	0	0.109	0	0	0.027	0.125	0.09	0.015
rs2981963	chr6:167630537	188.4403	UNC93A	0	0.003	0.01	0.01	0	0.06	0	0	0.016	0.041	0.057	0.006
rs1532145	chr6:168299050	190.6142		0	0	0.016	0.01	0	0.007	0	-0.006	0	0	0.004	-0.006
rs1884477	chr6:168694014	191.6161	SMOC2	0	0	0.032	0.01	0	0.001	0	-0.01	0.004	0	0	-0.01
rs9364286	chr6:168898564	192.0297		0	0	0.04	0.01	0	0	0	-0.01	0.007	0	0.001	-0.01
rs4708557	chr6:169081526	192.3618		0	0	0.036	0.01	0	0	0	-0.006	0.019	0	0.007	-0.006
rs727619	chr6:170548119	194.0313	FAM120B	0	0	0.04	0.01	0	0	0	0	0.114	0	0.08	0.03
rs909475	chr6:170655714	194.0639		0	0	0.04	0.01	0	0	0	0	0.115	0	0.081	0.031
rs909472	chr6:170656108	194.0641		0	0	0.04	0.01	0	0	0	0	0.115	0	0.081	0.031
rs1474555	chr6:170674695	194.0702		0	0	0.04	0.01	0	0	0	0	0.115	0	0.081	0.031
rs756519	chr6:170692787	194.0805	PSMB1	0	0	0.04	0.01	0	0	0	0	0.115	0	0.081	0.031
rs2076318	chr6:170720350	194.1075	TBP	0	0	0.04	0.01	0	0	0	0	0.116	0	0.081	0.031
rs8770	chr6:170728456	194.1154	PDCD2	0	0	0.04	0.01	0	0	0	0	0.116	0	0.081	0.031

Table Legend: Tabular display of linkage analysis results for 12 different phenotype by genotype models across the chromosome. The yellow row marks the location of the selected gene, and the whitened rows correspond to 20 Mb
around the gene.

References

Badner JA, Koller D, Foroud T, Edenberg H, Nurnberger JI Jr, Zandi PP, Willour VL, McMahon FJ, Potash JB, Hamshere M, Grozeva D, Green E, Kirov G, Jones I, Jones L, Craddock N, Morris D, Segurado R, Gill M, Sadovnick D, Remick R, Keck P, Kelsoe J, Ayub M, MacLean A, Blackwood D, Liu CY, Gershon ES, McMahon W, Lyon GJ, Robinson R, Ross J, Byerley W. Genome-wide linkage analysis of 972 bipolar pedigrees using single-nucleotide polymorphisms. Mol Psychiatry. 2012 Jul;17(8):818-26. doi: 10.1038/mp.2011.89. Epub 2011 Jul 19. PubMed PMID: 21769101

Metamoodics Gene Information

BP - Genomewide Linkage Studies for MAP3K5

View in Genome Browser

Description

Results Figure

Results Table

References