Metamoodics Gene Information

 

  Chromosome: chr22    Cytoband: q11.21    Gene: COMT

 

MD - Genomewide Expression Studies for COMT


 

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Description

 
Shown here are the results for gene COMT from a meta-analysis of genomewide expression studies of bipolar disorder using microarrays with autopsy brain samples from humans. Details of the methods for carrying out the meta-analysis are provided here.

 

 

Results Figure

 
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Figure Legend: The figure shows a Forest Plot with the estimated fold change of gene expression comparing cases and controls and 95% confidence interval for each study. Details of the results are provided in the Results Table below.

 

 

Results Table

 

 

 

STUDYBRAIN_REGIONARRAY_PLATFORMSEBETA_EST.FC95%_CIPVALFDR_PVALPROBESET
AltarCFrontalBA46.10HGU133A0.06610.2943 1.23[1.12,1.34]0.0002460.000518213981_at
KatoBFrontalBA10HGU95AV20.0744-0.0356-1.03[-1.13,1.08]0.6360.99634651_at
KemetherThalamusHGU133P0.0739-0.0569-1.04[-1.15,1.06]0.4490.96213981_at
SklarAFrontalBA8.9HGU95AV20.12120.0149 1.01[-1.17,1.19]0.9030.951134651_at
SokolovTemporalCortexHGU95A0.0456-0.0167-1.01[-1.08,1.05]0.7180.94234651_at

 

 

References

 

Systematic Review of Genome-wide Gene Expression Studies of Bipolar Disorder Fayaz Seifuddin, Mehdi Pirooznia, Jennifer T. Judy, Fernando S. Goes, James B. Potash and Peter P. Zandi. Manuscript submitted.