Metamoodics Gene Information

 

  Chromosome: chr13    Cytoband: q33.2    Gene: DAOA

 

MD - Genomewide Linkage Studies for DAOA


 

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Description

 
Shown here are the results for gene DAOA from a genomewide linkage analysis of major depression carried out with 656 families and including 1,494 informative all possible affected relative pairs genotyped at 418 microsatellite markers (Holmans et al. 2007; American Journal of Psychiatry)
 
Details of the methods for the linkage analysis are provided in methods section.

 

 

Results Figure

 
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Figure Legend: Graphical display of linkage analysis results for 2 different analytic models across the chromosome.
The yellow line marks the location of the selected gene on the chromosome, and the white window
shows 20 Mb around the gene.

Linear: Linear model with Spairs scoring function and equal weighting for all families
Exponential: Exponential model with Spairs scoring function and equal weighting for all families

 

 

 

 

Results Table

 

 


Marker chr:pos_bp (hg18) pos_cM Gene(s) dhat LOD (lin) NPL (lin) Zlr (lin) LOD (exp) NPL (exp) Zlr (exp)      
D13S787Achr13:232787210   -0.01120.0098-0.1566-0.21230.0094-0.1566-0.2083
D13S1243Bchr13:237059622.27   -0.00250.0005-0.0379-0.04960.0005-0.0379-0.0485
D13S217Achr13:2826979013.23   0.05810.3241.00761.22150.32541.00761.2242
D13S217Bchr13:2827015513.24   0.05810.32421.0081.22180.32561.0081.2245
D13S1493Achr13:3290669022.82   0.03790.16170.76970.86290.17720.76970.9032
D13S1493Bchr13:3290725722.83   0.03780.1610.76820.86110.17640.76820.9013
D13S894Achr13:3763645629.6   -0.03870.1722-0.79-0.89050.181-0.79-0.913
D13S894Bchr13:3763672429.61   -0.03880.173-0.7921-0.89270.1819-0.7921-0.9153
D13S325Achr13:4207124935.44   -0.06140.4595-1.3192-1.45470.4891-1.3192-1.5008
D13S325Bchr13:4207157135.45   -0.06140.4595-1.3192-1.45470.4891-1.3192-1.5008
D13S788Achr13:5079062345.9   -0.05870.4084-1.2323-1.37150.428-1.2323-1.404
D13S788Bchr13:5079094945.91   -0.05870.4081-1.2319-1.37090.4277-1.2319-1.4034
D13S800Achr13:7277264958.83   -0.03450.132-0.6809-0.77960.1405-0.6809-0.8044
D13S800Bchr13:7277304158.84   -0.03440.1317-0.68-0.77860.1401-0.68-0.8033
D13S317Achr13:8162003367.71   0.000200.00430.004800.00430.005
D13S317Bchr13:8162031567.72   0.000200.00460.005200.00460.0053
D13S793Achr13:9674976381.02   0.04360.20640.85310.9750.21590.85310.9971
D13S793Bchr13:9675004281.03   0.04370.20730.85490.9770.21680.85490.9991
D13S779Achr13:10030194886.82   0.07860.62231.43741.69290.62581.43741.6976
D13S779Bchr13:10030230586.83   0.07850.62221.43721.69270.62571.43721.6975
- chr13:104916364                
D13S796Achr13:106686855100.73   0.06470.48171.34151.48940.50541.34151.5256
D13S796Bchr13:106687142100.74   0.06470.48131.34121.48880.5051.34121.525
D13S1265Achr13:108126457104.88   0.04060.1940.8610.94520.20030.8610.9604
D13S1265Bchr13:108126828104.89   0.04050.19340.85960.94360.19960.85960.9588
D13S285Achr13:111843382114.84   -0.02430.063-0.4613-0.53840.0634-0.4613-0.5402
D13S285Bchr13:111843564114.85   -0.02440.0632-0.4623-0.53960.0637-0.4623-0.5414
Table Legend: Tabular display of linkage analysis results for linear and exponential models with the Spairs scoring
function across the chromosome. The yellow row marks the location of the selected gene, and the whitened
rows correspond to the region 20 Mb around the gene.

 

 

 

References