Metamoodics Gene Information

 

  Chromosome: chr3    Cytoband: p26.1    Gene: GRM7

 

MD - Genomewide Linkage Studies for GRM7


 

View in Genome Browser

Description

 
Shown here are the results for gene GRM7 from a genomewide linkage analysis of major depression carried out with 656 families and including 1,494 informative all possible affected relative pairs genotyped at 418 microsatellite markers (Holmans et al. 2007; American Journal of Psychiatry)
 
Details of the methods for the linkage analysis are provided in methods section.

 

 

Results Figure

 
Download:
Figure Legend: Graphical display of linkage analysis results for 2 different analytic models across the chromosome.
The yellow line marks the location of the selected gene on the chromosome, and the white window
shows 20 Mb around the gene.

Linear: Linear model with Spairs scoring function and equal weighting for all families
Exponential: Exponential model with Spairs scoring function and equal weighting for all families

 

 

 

 

Results Table

 

 


Marker chr:pos_bp (hg18) pos_cM Gene(s) dhat LOD (lin) NPL (lin) Zlr (lin) LOD (exp) NPL (exp) Zlr (exp)      
D3S2387Achr3:10111790   -0.05330.2862-0.9531-1.1480.2934-0.9531-1.1624
D3S2387Bchr3:10114690.01   -0.05330.2861-0.9532-1.14790.2934-0.9532-1.1624
D3S1560Achr3:402390013.75   -0.06510.4597-1.2404-1.4550.4448-1.2404-1.4312
D3S1560Bchr3:402428813.76   -0.06510.4596-1.2405-1.45490.4447-1.2405-1.4311
D3S1304Achr3:689424117.32   -0.05470.2886-0.9325-1.15280.2713-0.9325-1.1178
D3S4545Achr3:855980621.16   -0.02410.0602-0.4461-0.52670.0555-0.4461-0.5056
D3S4545Bchr3:856040621.17   -0.0240.0602-0.4459-0.52650.0554-0.4459-0.5053
D3S1259Achr3:1207368032.7   0.01250.01580.22660.26970.01430.22660.257
D3S1259Bchr3:1207392432.71   0.01250.01580.22630.26950.01430.22630.2567
D3S3038Achr3:2192440341.09   0.03330.10740.58170.70320.10250.58170.6869
D3S3038Bchr3:2192471941.1   0.03330.10780.5830.70470.10290.5830.6885
D3S2432Achr3:3214018155.24   0.03180.12380.70160.7550.13190.70160.7794
D3S2432Bchr3:3214046455.25   0.03170.12340.70080.7540.13160.70080.7784
D3S1768Achr3:3459933357.76   0.0270.08760.5840.63530.09260.5840.6531
D3S1768Bchr3:3459963457.77   0.0270.08770.5840.63530.09260.5840.6532
D3S2409Achr3:4939308766.18   0.05930.35111.0661.27150.34871.0661.2671
D3S2409Bchr3:4939321166.19   0.05940.35121.06611.27170.34871.06611.2673
D3S1600Achr3:6329487880.21   0.03820.14470.68140.81640.13490.68140.7882
D3S1600Bchr3:6329530480.22   0.03820.14470.68140.81630.13490.68140.788
D3S4542Achr3:6446763083.95   0.03410.11480.60320.7270.10460.60320.6941
D3S4542Bchr3:6446795483.96   0.03410.11450.60250.72620.10440.60250.6934
D3S2406Achr3:7334106596.11   -0.01630.0355-0.3871-0.40430.0393-0.3871-0.4256
D3S2406Bchr3:7334140096.12   -0.01640.0356-0.3877-0.40490.0394-0.3877-0.4262
D3S4529Achr3:85935163104.53   -0.0150.0283-0.3356-0.36070.0313-0.3356-0.3799
D3S4529Bchr3:85935426104.54   -0.0150.0281-0.3348-0.35980.0312-0.3348-0.3789
D3S2459Achr3:103657973111.08   0.02690.08760.58520.6350.08780.58520.636
D3S2459Bchr3:103658162111.09   0.0270.0880.58660.63660.08830.58660.6375
D3S3045Achr3:108472546114.99   0.060.42721.2861.40260.42551.2861.3999
D3S3045Bchr3:108472851115   0.060.42761.28651.40320.42591.28651.4005
D3S2460Achr3:118885027122.6   0.03930.17530.80220.89860.17170.80220.8891
D3S2460Bchr3:118885341122.61   0.03930.17510.80180.8980.17150.80180.8886
D3S4523Achr3:122374752124.68   0.04030.17660.78820.90170.16830.78820.8804
D3S4523Bchr3:122375068124.69   0.04030.17660.78810.90180.16830.78810.8804
D3S1764Achr3:140670977143.23   0.02780.07540.48670.58920.0670.48670.5555
D3S1764Bchr3:140671375143.24   0.02780.07520.48630.58860.06690.48630.555
D3S1744Achr3:148575184151.06   0.01560.02530.29120.34110.02410.29120.333
D3S1744Bchr3:148575543151.07   0.01560.02540.29180.34180.02420.29180.3336
D3S1746Bchr3:153212428159.59   0.01160.01290.20040.24410.01210.20040.2365
D3S1763Achr3:168722374166.22   -0.01090.0126-0.2062-0.24110.0116-0.2062-0.2315
D3S1763Bchr3:168722661166.23   -0.0110.0127-0.2068-0.24170.0117-0.2068-0.2321
D3S3053Achr3:173233395171.6   0.01040.01150.19730.22990.01090.19730.2237
D3S3053Bchr3:173233918171.61   0.01050.01160.19820.23090.0110.19820.2246
D3S2427Achr3:177267389178.05   0.01170.01590.24320.27050.01620.24320.2727
D3S2427Bchr3:177267811178.06   0.01160.01580.24230.26940.0160.24230.2717
D3S1262Achr3:187706172192.03   -0.04370.2587-1.0395-1.09160.3069-1.0395-1.1888
D3S1262Bchr3:187706421192.04   -0.04370.2584-1.039-1.09090.3065-1.039-1.1881
D3S2398Achr3:190903682201.01   -0.0030.001-0.0619-0.06940.0011-0.0619-0.0718
D3S2398Bchr3:190903998201.02   -0.0030.001-0.0614-0.06880.0011-0.0614-0.0712
D3S2418Achr3:193799562208.4   0.01580.02680.30480.35150.02920.30480.3664
D3S2418Bchr3:193799869208.41   0.01580.02690.30510.35180.02920.30510.3668
D3S1311Achr3:198502372217.89   0.01510.02460.29130.33640.02660.29130.3501
D3S1311Bchr3:198502696217.9   0.01510.02460.29120.33630.02660.29120.35
Table Legend: Tabular display of linkage analysis results for linear and exponential models with the Spairs scoring
function across the chromosome. The yellow row marks the location of the selected gene, and the whitened
rows correspond to the region 20 Mb around the gene.

 

 

 

References