Metamoodics Gene Information

 

  Chromosome: chr16    Cytoband: q13    Gene: MT1G

 

MD - Genomewide Linkage Studies for MT1G


 

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Description

 
Shown here are the results for gene MT1G from a genomewide linkage analysis of major depression carried out with 656 families and including 1,494 informative all possible affected relative pairs genotyped at 418 microsatellite markers (Holmans et al. 2007; American Journal of Psychiatry)
 
Details of the methods for the linkage analysis are provided in methods section.

 

 

Results Figure

 
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Figure Legend: Graphical display of linkage analysis results for 2 different analytic models across the chromosome.
The yellow line marks the location of the selected gene on the chromosome, and the white window
shows 20 Mb around the gene.

Linear: Linear model with Spairs scoring function and equal weighting for all families
Exponential: Exponential model with Spairs scoring function and equal weighting for all families

 

 

 

 

Results Table

 

 


Marker chr:pos_bp (hg18) pos_cM Gene(s) dhat LOD (lin) NPL (lin) Zlr (lin) LOD (exp) NPL (exp) Zlr (exp)      
D16S3401Bchr16:1719300   0.01230.00990.14490.21380.00950.14490.2086
D16S2616Achr16:621262713.57   -0.00290.0008-0.0483-0.05970.0008-0.0483-0.0606
D16S2616Bchr16:621294113.58   -0.00290.0008-0.0488-0.06030.0008-0.0488-0.0612
D16S748Achr16:1204684828.37   0.01720.03190.33430.38360.03250.33430.3871
D16S748Bchr16:1204716128.38   0.01720.03220.33560.3850.03280.33560.3886
D16S3103Achr16:1738096336.83   0.01020.01210.21220.23620.01240.21220.2386
D16S3103Bchr16:1738129736.84   0.01020.0120.21140.23530.01230.21140.2377
D16S403Achr16:2294515144.44   -0.0290.0948-0.5829-0.66090.0938-0.5829-0.6574
D16S403Bchr16:2294532444.45   -0.02910.095-0.5836-0.66160.0941-0.5836-0.6581
D16S769Achr16:2606622450.85   -0.0450.2171-0.8589-10.2145-0.8589-0.9939
D16S769Bchr16:2606661050.86   -0.04510.2177-0.86-1.00130.2151-0.86-0.9953
D16S540Achr16:4763774657.27   -0.05010.2786-0.989-1.13260.2724-0.989-1.1201
D16S540Bchr16:4763813657.28   -0.050.2781-0.9882-1.13160.272-0.9882-1.1191
D16S3396Achr16:4974980860.5   -0.02690.0806-0.534-0.60920.0764-0.534-0.5933
D16S3396Bchr16:4975014660.51   -0.02690.0805-0.5337-0.60890.0764-0.5337-0.593
D16S3253Achr16:5334412069.04   -0.02950.0984-0.593-0.6730.1084-0.593-0.7066
D16S3253Bchr16:5334437769.05   -0.02950.0983-0.5928-0.67270.1083-0.5928-0.7063
- chr16:55258153                
C16S1385Bchr16:6287146278.64   -0.04990.223-0.7952-1.01340.2246-0.7952-1.0169
D16S2624Achr16:7029245686.11   -0.05430.2779-0.9105-1.13130.2782-0.9105-1.1319
D16S2624Bchr16:7029281786.12   -0.05430.2782-0.9109-1.13190.2785-0.9109-1.1325
D16S3096Achr16:7760239696.5   -0.05450.2715-0.8848-1.11830.2634-0.8848-1.1013
D16S3096Bchr16:7760270896.51   -0.05450.2711-0.8842-1.11730.263-0.8842-1.1004
D16S3091Achr16:81537950108.45   0.00180.00030.03250.03870.00030.03250.0394
D16S3091Bchr16:81538275108.46   0.00180.00030.03340.03980.00040.03340.0405
D16S539Achr16:84943534122.45   0.00230.00050.04240.04990.00050.04240.0502
D16S539Bchr16:84943929122.46   0.00230.00050.04160.0490.00050.04160.0493
D16S2621Achr16:86530829127.45   0.00360.00130.06440.0770.00130.06440.076
D16S2621Bchr16:86531379127.46   0.00360.00130.06480.07750.00130.06480.0765
Table Legend: Tabular display of linkage analysis results for linear and exponential models with the Spairs scoring
function across the chromosome. The yellow row marks the location of the selected gene, and the whitened
rows correspond to the region 20 Mb around the gene.

 

 

 

References