Metamoodics Gene Information

 

  Chromosome: chr11    Cytoband: q14.1    Gene: ODZ4

 

MD - Genomewide Linkage Studies for ODZ4


 

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Description

 
Shown here are the results for gene ODZ4 from a genomewide linkage analysis of major depression carried out with 656 families and including 1,494 informative all possible affected relative pairs genotyped at 418 microsatellite markers (Holmans et al. 2007; American Journal of Psychiatry)
 
Details of the methods for the linkage analysis are provided in methods section.

 

 

Results Figure

 
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Figure Legend: Graphical display of linkage analysis results for 2 different analytic models across the chromosome.
The yellow line marks the location of the selected gene on the chromosome, and the white window
shows 20 Mb around the gene.

Linear: Linear model with Spairs scoring function and equal weighting for all families
Exponential: Exponential model with Spairs scoring function and equal weighting for all families

 

 

 

 

Results Table

 

 


Marker chr:pos_bp (hg18) pos_cM Gene(s) dhat LOD (lin) NPL (lin) Zlr (lin) LOD (exp) NPL (exp) Zlr (exp)      
D11S1984Achr11:15232610   0.00850.00530.1120.15670.00530.1120.156
D11S2362Achr11:48687227.27   -0.00880.0083-0.1691-0.19550.0087-0.1691-0.2003
D11S2362Bchr11:48689977.28   -0.00870.0082-0.1686-0.19490.0087-0.1686-0.1997
D11S1999Achr11:1067652317.05   -0.00580.0037-0.1138-0.130.0037-0.1138-0.1305
D11S1999Bchr11:1067682717.06   -0.00580.0037-0.1139-0.13010.0037-0.1139-0.1306
D11S1981Achr11:1704264925.59   0.01030.0110.19050.22470.01060.19050.2205
D11S1981Bchr11:1704292825.6   0.01030.0110.19050.22470.01060.19050.2205
C11S348Achr11:26611911.6239.25   0.01970.03890.35380.42330.040.35380.4292
C11S348Bchr11:26618921.8639.26   0.01970.03890.35370.42320.040.35370.429
D11S1392Achr11:3459658050.64   -0.01530.0244-0.2862-0.33540.0254-0.2862-0.3423
D11S1392Bchr11:3459687250.65   -0.01520.0244-0.2862-0.33530.0254-0.2862-0.3422
D11S1993Bchr11:4356649559.21   0.01830.03340.32660.39210.03340.32660.3922
D11S1344Achr11:4612343563.51   0.04080.1730.76230.89250.1740.76230.8952
D11S1344Bchr11:4612380263.52   0.04080.17360.76360.89410.17460.76360.8968
D11S2371Achr11:7318272079.34   0.04340.18270.75720.91740.18590.75720.9252
D11S2371Bchr11:7318302279.35   0.04340.18250.75670.91680.18560.75670.9245
- chr11:78041975                
D11S2002Achr11:7964302987.25   0.03570.12470.62810.75780.12210.62810.7497
D11S2002Bchr11:7964331087.26   0.03570.12450.62740.75710.12180.62740.749
D11S2000Achr11:105063888105.18   -0.06790.5211-1.3616-1.54910.4977-1.3616-1.514
D11S2000Bchr11:105064214105.19   -0.06790.5204-1.3609-1.54810.4971-1.3609-1.513
D11S1391Achr11:110200193109.66   -0.04820.2546-0.9391-1.08280.2492-0.9391-1.0713
D11S1391Bchr11:110200550109.67   -0.04820.2543-0.9385-1.08220.2489-0.9385-1.0707
D11S1998Achr11:117202940119.99   0.01310.01610.22090.27220.01620.22090.273
D11S1998Bchr11:117203240120   0.01310.01630.22220.27380.01640.22220.2746
D11S4464Achr11:123131593130.43   0.0360.13290.66330.78220.13020.66330.7742
D11S4464Bchr11:123132230130.44   0.0360.13280.66330.78210.13010.66330.7741
D11S912Achr11:128129302137.93   0.02720.07960.52610.60550.07970.52610.6059
D11S912Bchr11:128129418137.94   0.02720.07960.52620.60560.07970.52620.606
D11S968Achr11:133323585152.45   -0.01020.0098-0.1717-0.21270.0104-0.1717-0.2184
D11S968Bchr11:133323827152.46   -0.01020.0098-0.1715-0.21260.0103-0.1715-0.2182
Table Legend: Tabular display of linkage analysis results for linear and exponential models with the Spairs scoring
function across the chromosome. The yellow row marks the location of the selected gene, and the whitened
rows correspond to the region 20 Mb around the gene.

 

 

 

References